Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727793 | 0.90 | AGTR2 (0.30) | — | |
| SCHEMBL7729565 | 0.82 | NR1H2 (0.36) | MMP2ANPEP | |
| SCHEMBL7731145 | 0.80 | ALDH1A1 (0.43) | MMP2ANPEP | |
| SCHEMBL7731141 | 0.80 | ALDH1A1 (0.43) | MMP2ANPEP | |
| SCHEMBL7722294 | 0.79 | ANPEP (0.52) | MMP2ANPEP | |
| SCHEMBL7722292 | 0.79 | ANPEP (0.52) | MMP2ANPEP | |
| SCHEMBL7722111 | 0.77 | BTK (0.38) | MMP2ANPEP | |
| SCHEMBL7722109 | 0.77 | BTK (0.38) | MMP2ANPEP | |
| SCHEMBL7726102 | 0.75 | MMP2 (0.42) | MMP2ANPEP | |
| SCHEMBL7726099 | 0.75 | MMP2 (0.42) | MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |