Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069805 | 0.87 | HRH3 (0.40) | HRH3SIRT2EPHX2MEN1KMT2A | |
| SCHEMBL6070089 | 0.79 | HRH3 (0.41) | HRH3SIRT2EPHX2MEN1KMT2A | |
| SCHEMBL6641184 | 0.73 | NOS1 (0.56) | SIRT2 | |
| SCHEMBL6137668 | 0.72 | FFAR4 (0.39) | HRH3 | |
| SCHEMBL6641453 | 0.72 | NOS3 (0.48) | MEN1KMT2A | |
| SCHEMBL4189350 | 0.69 | ALOX5 (0.47) | HRH3SIRT2EPHX2MEN1KMT2A | |
| SCHEMBL6069811 | 0.68 | PARP1 (0.35) | BRD4ALOX5 | |
| SCHEMBL10503367 | 0.67 | NUDT1 (0.62) | HRH3MEN1KMT2AALOX5OR51E2 | |
| SCHEMBL24211519 | 0.66 | SIRT2 (0.41) | HRH3SIRT2EPHX2MEN1KMT2A | |
| SCHEMBL5851730 | 0.66 | ACHE (0.42) | HRH3SIRT2EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391887-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; CARDIOVASCULAR DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-21 | — | — | US | disclosed |