SCHEMBL7730994

SCHEMBL7730994

CCc1ccc(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(C(F)(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.33
TSHR P16473 1/20 0.31
KIF11 P52732 2/20 0.30
TRPM8 Q7Z2W7 1/20 0.30
EPHX2 P34913 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7730346 0.92 KIF11 (0.34) FFAR1KIF11
SCHEMBL7722652 0.91 FFAR1 (0.32) FFAR1
SCHEMBL7735122 0.90 TSHR (0.32) FFAR1TSHRKIF11EPHX2NR1H4
SCHEMBL7730683 0.90 TSHR (0.35) TSHRKIF11EPHX2NR1H4EPHX1
SCHEMBL7731540 0.89 S1PR1 (0.32) FFAR1KIF11
SCHEMBL7729079 0.88 KIF11 (0.43) FFAR1KIF11
SCHEMBL7731389 0.88 DAO (0.36) FFAR1TSHRKIF11
SCHEMBL7730810 0.88 S1PR1 (0.34) FFAR1
SCHEMBL7733408 0.87 PPARG (0.32) TSHR
SCHEMBL7729284 0.87 KIF11 (0.32) TSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed