SCHEMBL7723039

SCHEMBL7723039

OC(CS)c1ncncn1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8570860 0.71
SCHEMBL15094791 0.70 TRPA1 (0.47) LMNA
SCHEMBL6923004 0.65 APLNR (0.30)
SCHEMBL367712 0.62 HSP90AA1 (0.31) HSP90AA1
SCHEMBL1574016 0.62 LMNA (0.39) LMNAHSP90AA1
SCHEMBL3819697 0.60 SMN1; SMN2 (0.50) LMNA
SCHEMBL2629790 0.60 HSP90AA1 (0.33) HSP90AA1
SCHEMBL2517677 0.60
SCHEMBL7523417 0.60
SCHEMBL2363479 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6398822-B1 MONO- OR DI-THIO SUBSTITUTED PYRIMIDINES OR TRIAZINES; SINGLE PACKAGE WITH REDUCING AGENT; IMPROVED COLOR SATURATION, DEVELOPMENT, AND CONSISTENCE; WASHFASTNESS; REDUCED HAIR DAMAGE AND SKIN IRRITATION THE PROCTOR & GAMBLE COMPANY 2002-06-04 US disclosed
EP-1067900-A1 PACKAGED HAIR COLOURING COMPOSITION North Carolina State University (US) 2001-01-17 EP disclosed
WO-1999051194-A1 PACKAGED HAIR COLOURING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1999-10-14 WO disclosed
WO-1999051195-A1 PACKAGED HAIR COLOURING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1999-10-14 WO disclosed