SCHEMBL7723690

SCHEMBL7723690

CC(=O)NC(C)c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 18/20 0.54
ACACA Q13085 6/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2655264 1.00 ACACB (0.54) ACACBACACA
SCHEMBL7010951 0.87 MMP9 (0.50) ACACBACACA
SCHEMBL30202565 0.86 ACACB (0.50) ACACBACACA
SCHEMBL20791689 0.85 L3MBTL1 (0.53)
SCHEMBL13778592 0.85 ACACB (0.56) ACACBACACA
SCHEMBL20791688 0.85 L3MBTL1 (0.53)
SCHEMBL10315770 0.84 L3MBTL1 (0.45)
SCHEMBL6966307 0.83 ACACB (0.54) ACACBACACA
SCHEMBL15022611 0.83 ACACB (0.54) ACACBACACA
SCHEMBL5987917 0.82 ACACB (0.54) ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4031552-B1 AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES TAKEDA PHARMACEUTICALS CO (JP) 2024-11-06 EP claimed
CN-122036790-A Chiral phosphine-acyclic phosphoramidite ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2026-05-15 CN disclosed
US-12370192-B2 Azole-fused pyridazin-3(2H)-one derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-29 US disclosed
US-20230028114-A1 AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-01-26 US disclosed
CN-107653233-B improved aminotransferase, its coding gene and genetically engineered bacterium for expressing said enzyme 泰州学院 2020-01-31 CN disclosed
CN-107108531-A 4-oxo-3, 4-dihydro-1, 2, 3-benzotriazines as modulators of GPR139 武田药品工业株式会社 2017-08-29 CN disclosed
US-9409865-B2 Modulators of methyl modifying enzymes, compositions and uses thereof Constellation_Pharmaceuticals, Inc. (US) 2016-08-09 US disclosed
US-20150315148-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. 2015-11-05 US disclosed
US-9051269-B2 Modulators of methyl modifying enzymes, compositions and uses thereof CONSTELLATION PHARMACEUTICALS, INC. (US) 2015-06-09 US disclosed
US-20140315949-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. (US) 2014-10-23 US disclosed
US-6399787-B1 TRANSITION METAL COMPLEX PENN STATE RESEARCH FOUNDATION 2002-06-04 US disclosed
EP-0812363-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE AMINES BAYER AG (DE) 2001-01-24 EP disclosed
WO-1999059721-A1 CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES THE PENN STATE RESEARCH FOUNDATION (US) 1999-11-25 WO disclosed
EP-0812363-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE AMINES BAYER AG (DE) 1997-12-17 EP disclosed
WO-1996027022-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE AMINES BAYER AKTIENGESELLSCHAFT (DE) 1996-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028114-A1 AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES GPR139, GPR119, GPR39 ACACB 4126/4885ACACA 4023/4885
US-12370192-B2 Azole-fused pyridazin-3(2H)-one derivatives GPR139, GPR119, GPR39 ACACB 4126/4885ACACA 4023/4885
US-20150315148-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF TET1, TET3, EHMT2 ACACB 610/4885ACACA 1171/4885
US-20140315949-A1 MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF TET1, TET3, EHMT2 ACACB 610/4885ACACA 1171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.