Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724237 | 1.00 | DRD2 (0.45) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7729407 | 0.90 | SIGMAR1 (0.48) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7729412 | 0.90 | SIGMAR1 (0.48) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7729521 | 0.81 | DRD2 (0.45) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7729514 | 0.81 | DRD2 (0.45) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7723172 | 0.80 | HTR2A (0.52) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7723166 | 0.80 | HTR2A (0.52) | DRD2DRD4SIGMAR1HTR7HTR2A | |
| SCHEMBL7724283 | 0.78 | CCR3 (0.50) | DRD2DRD4HTR7HTR2AHTR2C | |
| SCHEMBL7724290 | 0.78 | CCR3 (0.50) | DRD2DRD4HTR7HTR2AHTR2C | |
| SCHEMBL7729558 | 0.77 | CCR1 (0.60) | DRD4SIGMAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |