Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092638 | 0.79 | HNF4A (0.50) | ALDH1A1LMNAMAPTFABP5FABP7 | |
| SCHEMBL1934919 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTFABP5FABP7 | |
| SCHEMBL16253851 | 0.76 | KMT2A (0.51) | ALDH1A1LMNAMAPTFABP5FABP7 | |
| SCHEMBL10085227 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTFABP5FABP7 | |
| SCHEMBL2730698 | 0.74 | CA1 (0.57) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL18063249 | 0.74 | POLB (0.41) | ALDH1A1LMNAMAPTFABP5FABP7 | |
| SCHEMBL5089936 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTMYCL3MBTL1 | |
| SCHEMBL29901230 | 0.72 | FABP5 (0.59) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL44677 | 0.72 | FABP5 (0.59) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL29381061 | 0.72 | FABP5 (0.59) | FABP5FABP7EPHX2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403324-B1 | INCUBATING TARGET WITH AFFINITY MOLECULE CONTAINING REACTIVE FUNCTIONAL GROUP TO COVALENTLY BOND; RELEASING AFFINITY GROUP ENZYME INHIBITORS; BINDING PROTEIN AGONISTS AND ANTAGONISTS; SCREENING | CONJUCHEM, INC. (CA) | 2002-06-11 | — | — | US | disclosed |