Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092638 | 0.83 | HNF4A (0.50) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL1934919 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL7724549 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL16253851 | 0.73 | KMT2A (0.51) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL5037458 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL31670439 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL3552319 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL3552315 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| SCHEMBL3552317 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAL3MBTL1KMT2A | |
| Carbamic Acid SCHEMBL31095127 | 0.71 | KEAP1 (0.45) | MAPTLMNAKMT2AMEN1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088522-A1 | POLYMER-DES-ETHYL SUNITINIB CONJUGATES | NEKTAR THERAPEUTICS (US) | 2012-06-28 | — | — | WO | disclosed |