Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724582 | 0.89 | ELANE (0.47) | ELANEMAPTALDH1A1KMT2APOLB | |
| SCHEMBL7720733 | 0.89 | ELANE (0.51) | ELANEPTGS2MAPTALDH1A1KMT2A | |
| SCHEMBL7724572 | 0.86 | ELANE (0.44) | ELANESMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL7720726 | 0.86 | ELANE (0.44) | ELANESMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL7717492 | 0.83 | ELANE (0.46) | ELANEPTGS2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7721805 | 0.83 | ELANE (0.53) | ELANEPTGS2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7721775 | 0.82 | ELANE (0.51) | ELANEPTGS2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7695453 | 0.81 | MMP2 (0.40) | PTGS2SMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL7722363 | 0.80 | ELANE (0.43) | ELANESMN1; SMN2MAPTPOLBPKM | |
| SCHEMBL546386 | 0.80 | CES2 (0.45) | SMN1; SMN2MAPTALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |