SCHEMBL7724582

SCHEMBL7724582

Cc1ccc(C(=O)C(=[N+]=[N-])S(=O)(=O)c2ccc(OC(=O)C(C)C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
KMT2A Q03164 2/20 0.40
LMNA P02545 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
POLB P06746 2/20 0.35
PKM P14618 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
NOD2 Q9HC29 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724550 0.89 ELANE (0.53) ELANEKMT2ATDP1ALDH1A1MAPT
SCHEMBL7722385 0.89 LMNA (0.51) ELANEKMT2ALMNAALDH1A1MAPT
SCHEMBL7720726 0.87 ELANE (0.44) ELANETDP1MAPTPOLBPKM
SCHEMBL7724572 0.87 ELANE (0.44) ELANEKMT2ALMNATDP1ALDH1A1
SCHEMBL7720719 0.86 ELANE (0.40) ELANEKMT2ATDP1MAPTPOLB
SCHEMBL9010795 0.84 CES2 (0.48) KMT2ALMNAALDH1A1MAPTPOLB
SCHEMBL9010786 0.84 ALDH1A1 (0.52) KMT2ALMNATDP1ALDH1A1MAPT
SCHEMBL7724552 0.84 ELANE (0.45) ELANEKMT2ALMNATDP1ALDH1A1
SCHEMBL7722368 0.83 KMT2A (0.49) ELANEKMT2ALMNATDP1ALDH1A1
SCHEMBL7717492 0.82 ELANE (0.46) ELANEKMT2ALMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395446-B1 CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed