Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692156 | 0.85 | ADRB1 (0.57) | ADRB2ADRB1 | |
| SCHEMBL965291 | 0.85 | ADRB1 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4869389 | 0.81 | ADRB2 (0.48) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| Hydrochloric Acid SCHEMBL11692252 | 0.80 | ADRB2 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9767993 | 0.80 | ADRA2A (0.68) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1461292 | 0.80 | ADRA2A (0.68) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL30510977 | 0.79 | ADRB2 (0.65) | ADRB2ADRA2BADRA1AADRB1ADRB3 | |
| SCHEMBL29278698 | 0.79 | ADRA2A (0.66) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| Hydrochloric Acid SCHEMBL11670422 | 0.77 | ADRB3 (0.43) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4866776 | 0.77 | ADRB2 (0.53) | ADRB2ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362371-B1 | DIAMINES DISUBSTITUED WITH HYDROXYMETHYL HYDROXYETHYLPHENOL GROUPS; RESPIRATORY SYSTEM DISORDERS, NERVOUS SYSTEM INJURIES, AND PREMATURE LABOR | ADVANCED MEDICINE, INC. | 2002-03-26 | — | — | US | disclosed |