Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767993 | 1.00 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL29278698 | 0.98 | ADRA2A (0.66) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL4122825 | 0.81 | ADRB2 (0.50) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL2760850 | 0.81 | ADRA2A (0.66) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL29852847 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL9768011 | 0.81 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL4869389 | 0.80 | ADRB2 (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL7724551 | 0.80 | ADRB2 (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL7145434 | 0.79 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL28535211 | 0.78 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117481073-A | Construction method and application of fetal nerve tube malformation animal model | 安徽医科大学 | 2024-02-02 | — | — | CN | claimed |
| CN-106610405-A | Method for detecting contents of catecholamine substances and methoxy metabolites in human urine | 江苏省人民医院 | 2017-05-03 | — | — | CN | claimed |
| EP-2473199-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | Brain Watch Ltd. (IL) | 2012-07-11 | — | — | EP | claimed |
| US-20120156139-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEROF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2012-06-21 | — | — | US | claimed |
| WO-2011024156-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2011-03-03 | — | — | WO | claimed |
| US-20080287774-A1 | Magnetic Resonance Imaging and Spectroscopy Means and Methods Thereof | BRAIN WATCH LTD. (IL) | 2008-11-20 | — | — | US | claimed |
| CN-117481073-A | Construction method and application of fetal nerve tube malformation animal model | 安徽医科大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-106610405-A | Method for detecting contents of catecholamine substances and methoxy metabolites in human urine | 江苏省人民医院 | 2017-05-03 | — | — | CN | disclosed |
| EP-2473199-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | Brain Watch Ltd. (IL) | 2012-07-11 | — | — | EP | disclosed |
| US-20120156139-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEROF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2012-06-21 | — | — | US | disclosed |
| WO-2011024156-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2011-03-03 | — | — | WO | disclosed |
| CN-101395164-A | N- (phosphonoalkyl) -amino acids, derivatives and compositions thereof, and methods of use | SCOTT EUGENE J VAN YU RUEY J (US) | 2009-03-25 | — | — | CN | disclosed |
| US-20080287774-A1 | Magnetic Resonance Imaging and Spectroscopy Means and Methods Thereof | BRAIN WATCH LTD. (IL) | 2008-11-20 | — | — | US | disclosed |
| WO-2007052274-A2 | MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY MEANS AND METHODS THEREOF | BRAIN WATCH LTD. (IL) | 2007-05-10 | — | — | WO | disclosed |
| CN-1290823-C | Ketol fatty acid amide derivatives and plant growth regulators | SHISEIDO CO LTD (JP) | 2006-12-20 | — | — | CN | disclosed |
| CN-1680287-A | Ketol fatty acid amide derivatives and plant growth regulators | SHISEIDO CO LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1210278-C | Ketol fatty acid derivatives, preparation method and plant growth regulator | SHISEIDO CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| CN-1173926-C | Substituted 2-phenyl-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system and pharmaceutical compositions containing them | — | 2004-11-03 | — | — | CN | disclosed |
| CN-1419555-A | Ketol fatty acid derivatives and plant growth regulators | SHISEIDO CO LTD (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1296471-A | Substituted 2-phenyl-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system and pharmaceutical compositions containing them | PORTELA & CA SA (PT) | 2001-05-23 | — | — | CN | disclosed |