Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719994 | 0.76 | ACHE (0.38) | USP2DPP7RRM1ACHE | |
| SCHEMBL7720001 | 0.75 | LMNA (0.48) | LMNAPAX8 | |
| SCHEMBL7725797 | 0.72 | ACHE (0.34) | USP2DPP7RRM1CA2ACHE | |
| SCHEMBL7725791 | 0.72 | ACHE (0.34) | USP2DPP7RRM1CA2ACHE | |
| SCHEMBL9819777 | 0.72 | METAP2 (0.56) | — | |
| SCHEMBL11692574 | 0.70 | USP2 (0.69) | USP2DPP7RRM1CA2CA1 | |
| SCHEMBL7724600 | 0.69 | CYP2C9 (0.51) | MMP8LMNAPAX8 | |
| SCHEMBL7720015 | 0.68 | HPGD (0.43) | LMNAPAX8 | |
| SCHEMBL5491789 | 0.68 | USP2 (0.71) | USP2DPP7RRM1CA2CA1 | |
| SCHEMBL7725838 | 0.68 | GAA (0.44) | USP2LMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |