Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724590 | 0.80 | NAAA (0.40) | POLBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7720015 | 0.80 | HPGD (0.43) | POLBALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL7720013 | 0.79 | LMNA (0.39) | POLBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7723365 | 0.77 | ALDH1A1 (0.40) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7724598 | 0.76 | MGLL (0.49) | KDM4ELMNAPAX8NAAATSHR | |
| SCHEMBL7720001 | 0.74 | LMNA (0.48) | POLBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7724600 | 0.73 | CYP2C9 (0.51) | HDAC3POLBKMT2AHPGDLMNA | |
| SCHEMBL7719994 | 0.72 | ACHE (0.38) | USP2TSHR | |
| SCHEMBL7724416 | 0.71 | EGFR (0.44) | HDAC3POLBKMT2AALDH1A1HPGD | |
| SCHEMBL7724420 | 0.71 | EGFR (0.44) | HDAC3POLBKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |