Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724600 | 0.78 | CYP2C9 (0.51) | LMNAPAX8NAAAKDM4ACNR1 | |
| SCHEMBL7724420 | 0.76 | EGFR (0.44) | LMNAPAX8NAAAKMT2ATSHR | |
| SCHEMBL7724416 | 0.76 | EGFR (0.44) | LMNAPAX8NAAAKMT2ATSHR | |
| SCHEMBL7724590 | 0.75 | NAAA (0.40) | LMNAPAX8NAAAMEN1KMT2A | |
| SCHEMBL7724633 | 0.75 | USP2 (0.39) | LMNAPAX8 | |
| SCHEMBL7720015 | 0.75 | HPGD (0.43) | LMNAPAX8NAAACNR1CNR2 | |
| SCHEMBL7720013 | 0.74 | LMNA (0.39) | LMNAPAX8NAAAMEN1KMT2A | |
| SCHEMBL7725838 | 0.74 | GAA (0.44) | LMNAPAX8NAAAMEN1KMT2A | |
| SCHEMBL7719994 | 0.72 | ACHE (0.38) | TSHR | |
| SCHEMBL6436285 | 0.72 | CNR1 (0.69) | LMNAPAX8NAAACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |