SCHEMBL7724832

SCHEMBL7724832

N#COc1ccc(Oc2ccc(-c3ccc(Oc4ccc(OC#N)cc4)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GSTP1 P09211 1/20 0.34
PARP15 Q460N3 1/20 0.34
PARP10 Q53GL7 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
LTA4H P09960 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
CYP19A1 P11511 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184373 0.92 KMT2A (0.41) ALDH1A1MEN1KMT2ATSHRCYP3A4
SCHEMBL2589097 0.92 KMT2A (0.41) ALDH1A1MEN1KMT2ATSHRCYP3A4
SCHEMBL6056082 0.92 KMT2A (0.41) ALDH1A1MEN1KMT2ATSHRCYP3A4
SCHEMBL184515 0.92 MMP2 (0.34) ALDH1A1ESR2HPGDMAPK1RAB9A
SCHEMBL24787 0.84 CA1 (0.32) ALDH1A1TSHRCYP3A4KDM4EHPGD
SCHEMBL6056031 0.83 ALDH1A1 (0.48) ERBB2ALDH1A1MEN1KMT2ATDP1
SCHEMBL2404544 0.83 NAAA (0.46) ERBB2ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL9818364 0.83 LTA4H (0.57) ERBB2MEN1KMT2ATSHRGSTP1
SCHEMBL11774210 0.81 ESR2 (0.52) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL19771205 0.81 TEAD4 (0.52) ALDH1A1MEN1KMT2ATSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130075136-A1 RESIN COMPOSITION AND PREPREG, LAMINATE AND CIRCUIT BOARD THEREOF Elite Material Co., Ltd. (TW) 2013-03-28 US disclosed
US-8404764-B1 Resin composition and prepreg, laminate and circuit board thereof Elite Material Co., Ltd. (TW) 2013-03-26 US disclosed
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
US-6187417-B1 Substrate having high optical contrast and method of making same INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-13 US disclosed
EP-0147547-B1 PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1989-11-15 EP disclosed