Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 10/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829931 | 0.84 | FBP1 (0.41) | FBP1NPBWR1METAP2DGAT1KCNH2 | |
| SCHEMBL6826883 | 0.83 | EGLN1 (0.41) | FBP1CBFB | |
| SCHEMBL6826910 | 0.77 | NPBWR1 (0.51) | NPBWR1DGAT1KCNH2CBFB | |
| SCHEMBL6826904 | 0.75 | DGAT1 (0.40) | FBP1NPBWR1DGAT1KCNH2CBFB | |
| SCHEMBL6830141 | 0.74 | FBP1 (0.40) | FBP1CNR2PARP1 | |
| Water SCHEMBL1799673 | 0.73 | FBP1 (0.39) | FBP1CNR2PARP1 | |
| SCHEMBL6831937 | 0.70 | FBP1 (0.40) | FBP1PARP1 | |
| SCHEMBL6826888 | 0.70 | FBP1 (0.38) | FBP1 | |
| SCHEMBL21496711 | 0.70 | METAP2 (0.51) | HDAC11NPBWR1METAP2DGAT1KCNH2 | |
| SCHEMBL6829765 | 0.70 | MMP2 (0.56) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399782-B1 | ANTIDIABETIC AGENTS | METABASIS THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |