Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 2/20 | 0.32 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733526 | 1.00 | PTPN1 (0.39) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL7733813 | 1.00 | PTPN1 (0.39) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL7728185 | 0.89 | HSD17B10 (0.34) | PTPN1NR1H2NFKB1NFKB2RELA | |
| SCHEMBL7727961 | 0.89 | HSD17B10 (0.34) | PTPN1NR1H2NFKB1NFKB2RELA | |
| SCHEMBL7726101 | 0.89 | HSD17B10 (0.34) | PTPN1NR1H2NFKB1NFKB2RELA | |
| SCHEMBL7729049 | 0.88 | PTPN1 (0.38) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL7729134 | 0.88 | PTPN1 (0.38) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL7729324 | 0.85 | PTPN1 (0.34) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL21285787 | 0.83 | HSD11B1 (0.42) | PTPN1MMP2ANPEPNR1H2NR1H3 | |
| SCHEMBL8149676 | 0.82 | NFKB1 (0.34) | NR1H2NFKB1NFKB2RELACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |