Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728006 | 0.94 | FFAR1 (0.50) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL7873751 | 0.90 | F10 (0.45) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL7871985 | 0.89 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL8771122 | 0.88 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL6699688 | 0.86 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL15533196 | 0.85 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL15533197 | 0.85 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL692174 | 0.84 | LMNA (0.49) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL6777080 | 0.84 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR | |
| SCHEMBL9444908 | 0.82 | IDO1 (0.46) | SLC6A3SLC6A2SLC6A4SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410306-B1 | PREPARING PREFERENTIAL ENANTIMORPHS; OBTAIN CHEMICAL INTERMEDIATE, INCUBATE WITH ENZYMES, RECOVER PREFERENTIAL ENANTIMORPHS | SCHERING CORPORATION | 2002-06-25 | — | — | US | disclosed |
| WO-2000050628-A1 | ENANTIOSELECTIVE ENZYMATIC HYDROLYSIS OF 3-SUBSTITUTED ESTERS OF GLUTARIC ACID | SCHERING CORPORATION (US) | 2000-08-31 | — | — | WO | disclosed |