Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268167 | 0.94 | FNTA (0.47) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8903093 | 0.91 | GAA (0.46) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8770872 | 0.87 | LMNA (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL6974516 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL12268259 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL27462122 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL7728008 | 0.84 | SLC6A3 (0.49) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL5862004 | 0.84 | LMNA (0.47) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL7640086 | 0.83 | SLC6A3 (0.51) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 | |
| SCHEMBL9444890 | 0.81 | SLC6A3 (0.48) | LMNAALDH1A1HTTSMN1; SMN2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921080-B2 | Pig liver esterases | DSM IP ASSETS B.V. (NL) | 2014-12-30 | — | — | US | claimed |
| EP-2421962-B1 | IMPROVED PIG LIVER ESTERASES | DPX HOLDINGS BV (NL) | 2018-08-29 | — | — | EP | disclosed |
| US-8921080-B2 | Pig liver esterases | DSM IP ASSETS B.V. (NL) | 2014-12-30 | — | — | US | disclosed |
| US-20120100582-A1 | PIG LIVER ESTERASES | JLL/DELTA DUTCH NEWCO B.V. (NL) | 2012-04-26 | — | — | US | disclosed |
| EP-2421962-A1 | IMPROVED PIG LIVER ESTERASES | DSM IP Assets B.V. (NL) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010122175-A1 | IMPROVED PIG LIVER ESTERASES | DSM IP ASSETS B.V. (NL) | 2010-10-28 | — | — | WO | disclosed |