Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728458 | 1.00 | DRD2 (0.51) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL7722089 | 0.83 | TGM2 (0.42) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL7728461 | 0.82 | TGM2 (0.47) | TGM2LMNATP53HTR2AHTR2C | |
| SCHEMBL7722007 | 0.78 | TGM2 (0.42) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL7722003 | 0.78 | TGM2 (0.42) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL7722009 | 0.78 | TGM2 (0.42) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL29799597 | 0.76 | DRD2 (0.45) | DRD2TGM2DRD3HTR2A | |
| SCHEMBL7722092 | 0.75 | LMNA (0.40) | DRD2TGM2LMNATP53DRD3 | |
| SCHEMBL21996003 | 0.75 | LMNA (0.56) | LMNATP53 | |
| SCHEMBL7722097 | 0.75 | TGM2 (0.39) | TGM2LMNATP53HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |