Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722092 | 0.84 | LMNA (0.40) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7728458 | 0.83 | DRD2 (0.51) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7728454 | 0.83 | DRD2 (0.51) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7722007 | 0.81 | TGM2 (0.42) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7722003 | 0.81 | TGM2 (0.42) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7722009 | 0.81 | TGM2 (0.42) | TGM2LMNADRD2DRD3TP53 | |
| SCHEMBL7729067 | 0.76 | BTK (0.38) | — | |
| SCHEMBL7728349 | 0.76 | BTK (0.38) | — | |
| SCHEMBL7727553 | 0.76 | BTK (0.38) | — | |
| SCHEMBL7728341 | 0.76 | BTK (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |