Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333168 | 0.88 | CTSK (0.59) | CTSLCTSKCTSBCTSS | |
| SCHEMBL7333172 | 0.88 | CTSK (0.59) | CTSLCTSKCTSBCTSS | |
| SCHEMBL2066047 | 0.88 | CTSK (0.54) | CTSLCTSKCTSBCTSS | |
| SCHEMBL27857319 | 0.87 | CA1 (0.53) | CTSLCTSKCTSBCTSS | |
| SCHEMBL16494692 | 0.86 | SIRT2 (0.53) | CTSLCTSKCTSS | |
| SCHEMBL16494690 | 0.86 | SIRT2 (0.53) | CTSLCTSKCTSS | |
| SCHEMBL7302369 | 0.84 | PSMB1 (0.55) | CTSLCTSKCTSBCTSSCASP1 | |
| SCHEMBL27616333 | 0.83 | CTSL (0.61) | CTSLCTSKCTSBCTSSCASP1 | |
| SCHEMBL6139194 | 0.83 | CTSL (0.61) | CTSLCTSKCTSBCTSSCASP1 | |
| SCHEMBL2367306 | 0.82 | CTSK (0.67) | CTSLCTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |