Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494690 | 1.00 | SIRT2 (0.53) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL6198706 | 0.90 | SIRT2 (0.60) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| Trifluoroacetic Acid SCHEMBL6199887 | 0.87 | SIRT2 (0.57) | SIRT2SIRT1SIRT3TLR2CPB1 | |
| SCHEMBL7728708 | 0.86 | CTSL (0.55) | CTSLCTSSCTSK | |
| SCHEMBL17737201 | 0.86 | ITGB3 (0.58) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL1840309 | 0.86 | SIRT2 (0.61) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL1840311 | 0.86 | SIRT2 (0.61) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL6477219 | 0.86 | SIRT2 (0.61) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL9086439 | 0.86 | ITGB3 (0.60) | SIRT2SIRT1SIRT3PRSS1PRSS2 | |
| SCHEMBL5692870 | 0.86 | ITGB3 (0.60) | SIRT2SIRT1SIRT3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397488-B1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | FEDERAL STATE BUDGETARY INSTITUTION RES ZAKUSOV INSTITUTE OF PHARMACOLOGY (RU) | 2019-03-27 | — | — | EP | disclosed |
| US-9683014-B2 | Dipeptide mimetics of NGF and BDNF neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2017-06-20 | — | — | US | disclosed |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (RU) | 2015-04-23 | — | — | US | disclosed |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2011-12-22 | — | — | US | disclosed |
| EP-2397488-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | Uchrezhdenie Rossiiskoi Akademii Meditsynskikh Nauk Nauchno-issledovatelsky Institut Farmakologii Imeni V.V.Zakusova Ramn (RU) | 2011-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | SIRT2 942/4885SIRT1 816/4885SIRT3 618/4885 |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | SIRT2 942/4885SIRT1 816/4885SIRT3 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.