Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.52 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.52 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.52 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728766 | 1.00 | PSMB11 (0.52) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL7732179 | 0.85 | TERT (0.55) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL7732188 | 0.85 | TERT (0.55) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL7731020 | 0.83 | HTR1A (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL7731015 | 0.83 | HTR1A (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL30632573 | 0.76 | MEN1 (0.52) | ALDH1A1HPGDSMN1; SMN2GAAMEN1 | |
| SCHEMBL7730987 | 0.74 | ADORA2A (0.51) | ALDH1A1HPGDSMN1; SMN2GAAMEN1 | |
| SCHEMBL7730989 | 0.74 | ADORA2A (0.51) | ALDH1A1HPGDSMN1; SMN2GAAMEN1 | |
| SCHEMBL28460284 | 0.71 | FDPS (0.50) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28452461 | 0.71 | MEN1 (0.46) | ALDH1A1HPGDSMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628311-B1 | Xanthine-Derivatives as Antidepressants | KYOWA HAKKO KOGYO KK (JP) | 2002-04-24 | — | — | EP | disclosed |
| EP-0559893-B1 | XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1999-02-03 | — | — | EP | disclosed |
| EP-0565377-B1 | Therapeutic agents for use in the treatment of Parkinson's Disease | KYOWA HAKKO KOGYO KK (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5587378-A | ADMINISTERING A SUBSTITUTED XANTHINE COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5543415-A | ADMINISTERING A XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5484920-A | XANTHINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0628311-A1 | ANTIDEPRESSANT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0565377-A1 | Therapeutic agents for use in the treatment of parkinson's disease | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0559893-A1 | XANTHINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |