Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731319 | 0.91 | KIF11 (0.40) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7728933 | 0.90 | KIF11 (0.41) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7731389 | 0.90 | DAO (0.36) | KIF11FFAR1 | |
| SCHEMBL7730346 | 0.89 | KIF11 (0.34) | KIF11CYP11B1CYP11B2FFAR1 | |
| SCHEMBL7729745 | 0.88 | KIF11 (0.39) | KIF11CYP11B1CYP11B2FFAR1PPARA | |
| SCHEMBL7734971 | 0.88 | PRMT6 (0.39) | KIF11CYP11B1CYP11B2PRMT6FFAR1 | |
| SCHEMBL7730994 | 0.88 | FFAR1 (0.33) | KIF11FFAR1 | |
| SCHEMBL7722731 | 0.87 | RARB (0.41) | KIF11CYP11B1CYP11B2PPARAPPARG | |
| SCHEMBL7732093 | 0.87 | PRMT6 (0.36) | KIF11CYP11B1CYP11B2PRMT6PPARA | |
| SCHEMBL14749512 | 0.86 | TSHR (0.38) | KIF11PRMT6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |