Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730645 | 0.94 | ACHE (0.42) | ACHEBCHEGPR3MAPTKCNH2 | |
| SCHEMBL13104749 | 0.94 | ACHE (0.42) | ACHEBCHEGPR3MAPTKCNH2 | |
| SCHEMBL12829128 | 0.94 | ACHE (0.42) | ACHEBCHEGPR3MAPTKCNH2 | |
| SCHEMBL12152581 | 0.88 | ACHE (0.38) | ACHEBCHEKCNH2KIF11TSHR | |
| SCHEMBL10018707 | 0.88 | ACHE (0.38) | ACHEBCHEKCNH2KIF11TSHR | |
| SCHEMBL91415 | 0.87 | GPR3 (0.53) | ACHEBCHEGPR3FFAR4TP53 | |
| SCHEMBL25120146 | 0.86 | ACHE (0.58) | ACHEMAPTCCR6L3MBTL1KIF11 | |
| SCHEMBL13038185 | 0.86 | ACHE (0.58) | ACHEMAPTCCR6L3MBTL1KIF11 | |
| SCHEMBL7733360 | 0.85 | BCHE (0.44) | ACHEBCHEGPR3TP53EPHX2 | |
| Ammonia Solution, Strong SCHEMBL2444176 | 0.85 | GPR3 (0.52) | ACHEBCHEGPR3FFAR4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |