Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | UBE2I | P63279 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732103 | 0.76 | RAB9A (0.53) | MAPT | |
| SCHEMBL7732052 | 0.75 | RAB9A (0.43) | ALOX15MAPTPOLBTP53 | |
| SCHEMBL7732335 | 0.73 | CES1 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL7735917 | 0.72 | RAB9A (0.48) | MAPT | |
| SCHEMBL7732373 | 0.70 | TRPV1 (0.50) | MAPT | |
| SCHEMBL13036676 | 0.69 | ALOX15 (0.60) | SLC2A1PDE10AALOX15MAPT | |
| SCHEMBL7734004 | 0.69 | RAB9A (0.42) | ALOX15MAPTPOLBTP53 | |
| SCHEMBL7733996 | 0.68 | NPC1 (0.50) | MAPT | |
| SCHEMBL11413959 | 0.67 | ALOX15 (0.57) | SLC2A1PDE10AALOX15MAPTPOLB | |
| SCHEMBL6463446 | 0.67 | DAGLA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |