SCHEMBL7733586

SCHEMBL7733586

CC(C)(C)Oc1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=S(=O)([O-])c1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA7 P43166 1/20 0.33
MMP13 P45452 1/20 0.32
NR1I2 O75469 1/20 0.32
ABCB1 P08183 1/20 0.31
CA14 Q9ULX7 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
PPARA Q07869 1/20 0.31
MMP2 P08253 2/20 0.31
MMP9 P14780 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900930 0.89 PPARA (0.37) MEN1KMT2AMMP13ABCB1LMNA
SCHEMBL64769 0.85 HTT (0.44) MEN1KMT2ACA12CA1CA2
SCHEMBL65269 0.85 HTT (0.44) MEN1KMT2ACA12CA1CA2
SCHEMBL7741642 0.84 CYP19A1 (0.33) ACACBMEN1KMT2ACYP19A1CA12
SCHEMBL8316981 0.83 PPARA (0.33) ACACBMEN1KMT2AMMP13ABCB1
SCHEMBL8320141 0.83 PPARA (0.33) ACACBMEN1KMT2AMMP13ABCB1
SCHEMBL7738088 0.83 CA12 (0.41) CA12CA1CA2CA9CA7
SCHEMBL7741629 0.83 NR3C2 (0.44) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL7741631 0.83 MAOA (0.43) CA1CA2LMNAHTTSMN1; SMN2
SCHEMBL7738178 0.82 HSD11B1 (0.30) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed