SCHEMBL7738178

SCHEMBL7738178

CC(C)(C)Oc1ccccc1[S+](c1ccccc1)c1ccccc1.O=S(=O)([O-])c1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.30
HSD17B3 P37058 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733586 0.82 ACACB (0.34) CA12CA1CA2CA9CA14
SCHEMBL7738088 0.78 CA12 (0.41) HSD11B1CA12CA1CA2CA9
SCHEMBL7741631 0.78 MAOA (0.43) HSD11B1HSD17B3CA1CA2MAOA
SCHEMBL3194018 0.75 FFAR1 (0.34) HSD11B1
SCHEMBL5851079 0.74 HTR6 (0.46) CA12CA1CA2CA9CA14
SCHEMBL3197743 0.73 NPC1 (0.36)
SCHEMBL7741642 0.72 CYP19A1 (0.33) CA12CA1CA2CA9CA14
SCHEMBL3203856 0.71 AR (0.34) HSD11B1CA1CA2CA9
SCHEMBL5850133 0.71 KMT2A (0.40) CA12CA1CA2CA9
SCHEMBL3193372 0.71 PTGDR2 (0.35) HSD11B1HSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed