SCHEMBL7733592

SCHEMBL7733592

CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.O=S(=O)([O-])c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
MAPT P10636 1/20 0.45
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ACHE P22303 2/20 0.40
HSD11B1 P28845 2/20 0.39
RAB9A P51151 2/20 0.39
BCHE P06276 1/20 0.39
NPC1 O15118 1/20 0.39
RECQL P46063 1/20 0.39
PSEN1 P49768 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452774 0.88 ALDH1A1 (0.46) ALDH1A1MAPTLMNASMN1; SMN2HTT
SCHEMBL7733558 0.85 CA2 (0.50) LMNACA1CA2CA12CA9
SCHEMBL8131241 0.85 ALDH1A1 (0.52) ALDH1A1MAPTLMNASMN1; SMN2HTT
SCHEMBL7738075 0.84 NR3C2 (0.50) ALDH1A1MAPTLMNASMN1; SMN2HTT
SCHEMBL7738770 0.83 ALDH1A1 (0.43) ALDH1A1MAPTLMNASMN1; SMN2HTT
SCHEMBL7738079 0.82 ALDH1A1 (0.39) ALDH1A1HTTPOLBCA1CA2
Phenylmethanesulfonic Acid SCHEMBL9078676 0.81 ALDH1A1 (0.45) ALDH1A1MAPTLMNASMN1; SMN2CA1
SCHEMBL7739943 0.81 MAOA (0.43) ALDH1A1MAPTLMNASMN1; SMN2HTT
SCHEMBL2964585 0.80 CA2 (0.48) ALDH1A1LMNASMN1; SMN2HTTCA1
SCHEMBL7741651 0.80 LTA4H (0.57) ALDH1A1LMNAHTTPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416928-B1 HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-09 US disclosed