Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735329 | 0.79 | LTB4R (0.51) | PPARGSLC6A9PTPN11PTPN1PTPN6 | |
| SCHEMBL27406195 | 0.76 | PPARG (0.53) | PPARGPTGESALOX5SLC6A9PTPN11 | |
| SCHEMBL27288709 | 0.74 | PTPN11 (0.74) | SLC6A9PTPN11PTPN1PTPN6MCL1 | |
| SCHEMBL7724935 | 0.74 | MEN1 (0.49) | PPARGSLC6A9PTPN11PPARAPPARD | |
| SCHEMBL12121775 | 0.72 | PTPN11 (0.60) | PTPN11PTPN1PTPN6MCL1 | |
| SCHEMBL27406194 | 0.71 | CYSLTR2 (0.46) | PPARGPTGESALOX5SLC6A9PTPN11 | |
| SCHEMBL8726708 | 0.70 | PTPN11 (0.51) | PPARGPTGESALOX5PTPN11PTPN1 | |
| SCHEMBL6271504 | 0.70 | SLC6A9 (0.74) | SLC6A9 | |
| SCHEMBL8273274 | 0.70 | SLC6A9 (0.70) | SLC6A9 | |
| SCHEMBL29111485 | 0.69 | ESR1 (0.51) | ALOX5PTPN11ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |