Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734525 | 0.85 | HDAC6 (0.57) | HDAC6HSPA8ADKMEN1KMT2A | |
| SCHEMBL7734332 | 0.83 | HDAC6 (0.50) | HDAC6IDH1HSPA8ADK | |
| SCHEMBL7114052 | 0.82 | HDAC6 (0.49) | HDAC6IDH1SMN1; SMN2HSPA8MEN1 | |
| SCHEMBL7740717 | 0.81 | TDP1 (0.38) | IDH1ALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7215020 | 0.80 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL7738034 | 0.80 | HDAC6 (0.56) | HDAC6SMN1; SMN2HSPA8 | |
| SCHEMBL7215024 | 0.80 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL10308324 | 0.80 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL7742258 | 0.78 | HDAC6 (0.57) | HDAC6ALDH1A1SMN1; SMN2GAAHSPA8 | |
| SCHEMBL7733484 | 0.78 | HDAC6 (0.49) | HDAC6IDH1HSPA8ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |