Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734310 | 0.81 | HDAC6 (0.50) | TDP1PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL7740696 | 0.80 | ALDH1A1 (0.36) | TDP1PRKACARPS6KB1GSK3BROCK1 | |
| SCHEMBL7739180 | 0.80 | HDAC6 (0.49) | ADKHSPA8ADORA3 | |
| SCHEMBL7739934 | 0.80 | HDAC6 (0.49) | ADKHSPA8ADORA3 | |
| SCHEMBL7124713 | 0.80 | HDAC6 (0.49) | ADKHSPA8ADORA3 | |
| SCHEMBL7739177 | 0.80 | HDAC6 (0.49) | ADKHSPA8ADORA3 | |
| SCHEMBL7739913 | 0.73 | SLC15A1 (0.38) | ADKHSPA8KMT2AADORA3 | |
| SCHEMBL7734525 | 0.69 | HDAC6 (0.57) | ADKHTTHSPA8KMT2A | |
| SCHEMBL25443596 | 0.69 | ALDH1A1 (0.55) | TDP1ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL8189109 | 0.68 | HDAC6 (0.51) | ADKHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |
| EP-0970100-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035977-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |