Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351544 | 0.92 | HSD11B1 (0.40) | ALDH1A1HSD11B1NPSR1MEN1KMT2A | |
| SCHEMBL7457627 | 0.90 | ALDH1A1 (0.42) | ALDH1A1PKML3MBTL1NPSR1RBP4 | |
| SCHEMBL1732678 | 0.90 | HSD11B1 (0.41) | ALDH1A1HSD11B1PKML3MBTL1NPSR1 | |
| SCHEMBL6559746 | 0.88 | HSD11B1 (0.40) | ALDH1A1HSD11B1NPSR1MEN1KMT2A | |
| SCHEMBL964124 | 0.86 | HSD11B1 (0.41) | ALDH1A1HSD11B1PKML3MBTL1MEN1 | |
| SCHEMBL5608428 | 0.80 | MEN1 (0.46) | HSD11B1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7735482 | 0.80 | PKM (0.44) | ALDH1A1HSD11B1PKMNPSR1MEN1 | |
| SCHEMBL8197101 | 0.80 | MEN1 (0.46) | HSD11B1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL282760 | 0.79 | PKM (0.42) | ALDH1A1PKML3MBTL1MEN1KMT2A | |
| SCHEMBL29281855 | 0.79 | HSD11B1 (0.34) | ALDH1A1HSD11B1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990634-B1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | DAICEL CHEM (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-6429314-B1 | USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| EP-0990634-A1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |