Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741706 | 0.78 | HTR1A (0.53) | HTR1A | |
| SCHEMBL7740272 | 0.73 | HTR1A (0.66) | MTNR1AMTNR1BNQO2HTR2CHTR1A | |
| SCHEMBL7740264 | 0.73 | MTNR1B (0.69) | MTNR1AMTNR1BNQO2HTR1A | |
| SCHEMBL4689360 | 0.72 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL3575547 | 0.68 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL3583911 | 0.68 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL1612720 | 0.68 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL2296949 | 0.67 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL4686039 | 0.67 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL11927531 | 0.67 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |