Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 18/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 18/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740269 | 0.87 | MTNR1B (0.61) | HTR1AMTNR1BMTNR1ANQO2 | |
| SCHEMBL7735727 | 0.82 | MTNR1A (0.65) | HTR1AMTNR1BMTNR1ANQO2 | |
| SCHEMBL7743293 | 0.80 | HTR1A (1.00) | HTR1AMTNR1BMTNR1AHTR2C | |
| SCHEMBL7740264 | 0.79 | MTNR1B (0.69) | HTR1AMTNR1BMTNR1ANQO2 | |
| SCHEMBL6631892 | 0.79 | MTNR1B (1.00) | MTNR1BMTNR1AHTR2C | |
| SCHEMBL6633692 | 0.79 | MTNR1B (1.00) | MTNR1BMTNR1AHTR2C | |
| SCHEMBL7741718 | 0.78 | HTR1A (0.57) | HTR1AMTNR1BMTNR1ANQO2 | |
| SCHEMBL7741709 | 0.78 | HTR1A (0.81) | HTR1AMTNR1BMTNR1AHTR2CNQO2 | |
| SCHEMBL7743295 | 0.73 | HTR1A (0.63) | HTR1AMTNR1BMTNR1A | |
| SCHEMBL7735741 | 0.73 | MTNR1A (0.51) | HTR1AMTNR1BMTNR1AHTR2CNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |