Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733875 | 0.91 | LMNA (0.41) | MAPTPOLBSIRT2LMNAKMT2A | |
| SCHEMBL7735662 | 0.87 | NPC1 (0.42) | MAPTLMNAKMT2AMEN1TP53 | |
| SCHEMBL7734848 | 0.85 | MAPT (0.38) | MAPTSIRT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7734102 | 0.84 | TSHR (0.43) | MAPTPOLBLMNAKMT2AMEN1 | |
| SCHEMBL7734337 | 0.83 | NLRP3 (0.36) | MAPTSIRT2LMNAL3MBTL1 | |
| SCHEMBL7734855 | 0.83 | SIRT2 (0.34) | SIRT2KMT2AMEN1 | |
| SCHEMBL7734231 | 0.81 | RAB9A (0.40) | POLBSIRT2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7734700 | 0.79 | NLRP3 (0.35) | MAPTLMNAL3MBTL1 | |
| SCHEMBL7735189 | 0.78 | GAA (0.36) | MAPTPOLBSIRT2KMT2AMEN1 | |
| SCHEMBL7734093 | 0.78 | SIRT2 (0.37) | MAPTSIRT2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |