Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735189 | 0.92 | GAA (0.36) | SIRT2MEN1KMT2A | |
| SCHEMBL7734337 | 0.88 | NLRP3 (0.36) | SIRT2MTNR1AMTNR1BAKR1B1 | |
| SCHEMBL7735662 | 0.85 | NPC1 (0.42) | MEN1KMT2A | |
| SCHEMBL7733875 | 0.84 | LMNA (0.41) | SIRT2MTNR1AMTNR1BAKR1B1MEN1 | |
| SCHEMBL7734700 | 0.84 | NLRP3 (0.35) | MTNR1AMTNR1BAKR1B1 | |
| SCHEMBL7734093 | 0.83 | SIRT2 (0.37) | SIRT2MTNR1AMTNR1BAKR1B1MEN1 | |
| SCHEMBL7734848 | 0.83 | MAPT (0.38) | SIRT2AKR1B1MEN1KMT2A | |
| SCHEMBL7735795 | 0.83 | MAPT (0.45) | SIRT2MEN1KMT2A | |
| SCHEMBL7734231 | 0.81 | RAB9A (0.40) | SIRT2KMT2A | |
| SCHEMBL7734862 | 0.77 | SLC22A12 (0.41) | AKR1B1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |