Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734337 | 0.88 | NLRP3 (0.36) | SSTR2SSTR4SIRT2L3MBTL1 | |
| SCHEMBL7735189 | 0.86 | GAA (0.36) | RAB9ANPC1POLBKMT2ASIRT2 | |
| SCHEMBL7733875 | 0.85 | LMNA (0.41) | POLBKMT2ASIRT2HPGD | |
| SCHEMBL7733878 | 0.84 | RAB9A (0.43) | RAB9ANPC1PKMPOLB | |
| SCHEMBL7734700 | 0.84 | NLRP3 (0.35) | SSTR2SSTR4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7734848 | 0.81 | MAPT (0.38) | KMT2ASIRT2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7734855 | 0.81 | SIRT2 (0.34) | KMT2ASIRT2 | |
| SCHEMBL7734093 | 0.81 | SIRT2 (0.37) | RAB9ANPC1SSTR2SSTR4KMT2A | |
| SCHEMBL7735795 | 0.81 | MAPT (0.45) | RAB9APOLBKMT2ASIRT2ALDH1A1 | |
| SCHEMBL7735662 | 0.81 | NPC1 (0.42) | RAB9ANPC1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |