Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | PKM | P14618 | 1/20 | 0.84 |
| ▸ | PPARG | P37231 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.84 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.84 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.82 |
| ▸ | PGR | P06401 | 7/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.82 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.82 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.82 |
| ▸ | IL5 | P05113 | 1/20 | 0.82 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.82 |
| ▸ | AR | P10275 | 1/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.82 |
| ▸ | MMP9 | P14780 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751385 | 1.00 | ALDH1A1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL17151413 | 1.00 | ALDH1A1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL4448853 | 0.94 | NR3C1 (0.82) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL5396842 | 0.93 | NR3C1 (0.81) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL26227694 | 0.93 | NR3C1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL13491403 | 0.93 | NR3C1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL13368103 | 0.93 | NR3C1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL13524508 | 0.93 | NR3C1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL27106939 | 0.93 | NR3C1 (0.84) | ALDH1A1PKMPPARGHTTNCOA2 | |
| SCHEMBL27072506 | 0.92 | NR3C1 (0.79) | ALDH1A1PKMPPARGHTTNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | claimed |
| US-20230099074-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME LLC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230099074-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME LLC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20200164085-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME LLC | 2020-05-28 | — | — | US | disclosed |
| US-10550190-B2 | Phosphate based linkers for intracellular delivery of drug conjugates | MERCK SHARP & DOHME CORP. (US) | 2020-02-04 | — | — | US | disclosed |
| US-10550190-B2 | Phosphate based linkers for intracellular delivery of drug conjugates | MERCK SHARP & DOHME CORP. (US) | 2020-02-04 | — | — | US | disclosed |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-06-29 | — | — | US | disclosed |
| WO-2017062271-A2 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | MERCK SHARP & DOHME CORP. (US) | 2017-04-13 | — | — | WO | disclosed |
| US-6423340-B1 | GASTROINTESTINAL DISORDERS, CROHN'S COLITIS | AKTIEBOLAGET DRACO (SE) | 2002-07-23 | — | — | US | disclosed |
| US-5643602-A | TIME RELEASE PELLETS FOR INTESTINES | ASTRA AKTIEBOLAG (SE) | 1997-07-01 | — | — | US | disclosed |
| EP-0502092-B1 | ORAL COMPOSITION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | DRACO AB (SE) | 1995-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200164085-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | CD44, FCGR2A, TNF | ALDH1A1 997/4885PKM 3114/4885PPARG 3936/4885 |
| US-20170182181-A1 | PHOSPHATE BASED LINKERS FOR INTRACELLULAR DELIVERY OF DRUG CONJUGATES | CD47, PLPBP, CHERP | ALDH1A1 4114/4885PKM 1271/4885PPARG 4319/4885 |
| US-20230099074-A1 | ANTIBODY DRUG CONJUGATE FOR ANTI-INFLAMMATORY APPLICATIONS | CD44, FCGR2A, TNF | ALDH1A1 997/4885PKM 3114/4885PPARG 3936/4885 |
| US-10550190-B2 | Phosphate based linkers for intracellular delivery of drug conjugates | CD47, PLPBP, CHERP | ALDH1A1 4114/4885PKM 1271/4885PPARG 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.