Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735941 | 0.83 | CA1 (0.39) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL7933507 | 0.83 | LOXL2 (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL21962901 | 0.81 | KMT2A (0.39) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL7735252 | 0.81 | CA2 (0.40) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9826820 | 0.81 | RXFP1 (0.44) | ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL18896036 | 0.80 | KMT2A (0.43) | ALDH1A1KDM4EHSD17B10TSHRKMT2A | |
| SCHEMBL7935254 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL7727241 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTTSHRCA1CA2 | |
| SCHEMBL7563166 | 0.78 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL18879564 | 0.77 | HDAC3 (0.37) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410483-B1 | CONTROLLING WEEDS, GRASSES; COMPOUND CONTAINING PYRIMIDINE RING | HOECHST SCHERING AGREVO GMBH (DE) | 2002-06-25 | — | — | US | disclosed |