SCHEMBL7933507

SCHEMBL7933507

COC(=O)c1ccc(CN)cc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.45
CA2 P00918 3/20 0.42
CA1 P00915 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 6/20 0.41
GAA P10253 4/20 0.41
MAPT P10636 4/20 0.41
HPGD P15428 4/20 0.41
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 3/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
GLA P06280 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ATM Q13315 1/20 0.37
CFTR P13569 1/20 0.37
KLKB1 P03952 1/20 0.36
ABL1 P00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735252 0.90 CA2 (0.40) LOXL2CA2CA1CA5ACA9
SCHEMBL7735941 0.86 CA1 (0.39) CA2CA1CA5ACA9ALDH1A1
SCHEMBL21962901 0.84 KMT2A (0.39) CA2CA1CA5ACA9ALDH1A1
SCHEMBL7736172 0.83 ALDH1A1 (0.39) CA2CA1CA5ACA9ALDH1A1
SCHEMBL7935254 0.83 SMN1; SMN2 (0.40) CA2CA1CA5ACA9ALDH1A1
SCHEMBL18896036 0.83 KMT2A (0.43) ALDH1A1KDM4EHSD17B10TSHRKMT2A
SCHEMBL29253953 0.83 CA2 (0.58) LOXL2CA2CA1CA5ACA9
SCHEMBL7875914 0.82 GAA (0.54) CA2CA1CA5ACA9ALDH1A1
SCHEMBL7727241 0.81 ALDH1A1 (0.39) CA2CA1CA9ALDH1A1MAPT
SCHEMBL18879564 0.80 HDAC3 (0.37) CA2CA1CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9693558-B2 Process for preparing a novel crystalline form of mesosulfuron-methyl and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-07-04 US disclosed
US-9693558-B2 Process for preparing a novel crystalline form of mesosulfuron-methyl and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-07-04 US disclosed
US-9693558-B2 Process for preparing a novel crystalline form of mesosulfuron-methyl and use of the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-07-04 US disclosed
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-06-08 US disclosed
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-06-08 US disclosed
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-06-08 US disclosed
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 US disclosed
WO-2017092477-A1 PROCESS FOR PREPARING NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 WO disclosed
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 US disclosed
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-08 US disclosed
US-9661851-B1 Synergistic herbicidal composition and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-30 US disclosed
US-9661851-B1 Synergistic herbicidal composition and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-30 US disclosed
US-9661851-B1 Synergistic herbicidal composition and use thereof ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2017-05-30 US disclosed
US-6239306-B1 Phenylsulfonylureas, processes for their preparation, and their use as herbicides and plant growth regulations HOECHST SCHERING AGREVO GMBH (DE) 2001-05-29 US disclosed
US-5925597-A PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1999-07-20 US disclosed
EP-0723534-B1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-07-29 EP disclosed
US-5648315-A Phenylsulfonylureas, Processes for their-preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1997-07-15 US disclosed
EP-0723534-A1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1996-07-31 EP disclosed
WO-1995010507-A1 PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170156330-A1 PROCESS FOR PREPARING A NOVEL CRYSTALLINE FORM OF MESOSULFURON-METHYL AND USE OF THE SAME MPST, STS, SCLY LOXL2 2046/4885CA2 2254/4885CA1 891/4885
US-20170156332-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND USE THEREOF DDT, AS3MT, METTL3 LOXL2 960/4885CA2 744/4885CA1 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.