Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595494 | 0.81 | PLK1 (0.35) | SMN1; SMN2HPGDKMT2AMAPTMEN1 | |
| SCHEMBL7152266 | 0.77 | PDE4B (0.36) | SMN1; SMN2HPGDKMT2AMAPTMEN1 | |
| SCHEMBL439377 | 0.76 | BRD4 (0.37) | SMN1; SMN2HPGDKMT2ABRD4AKT2 | |
| SCHEMBL7070227 | 0.75 | BRD4 (0.36) | SMN1; SMN2HPGDKMT2ABRD4AKT2 | |
| SCHEMBL6957908 | 0.73 | CYP1A2 (0.38) | SMN1; SMN2HPGDKMT2ABRD4AKT2 | |
| SCHEMBL17180554 | 0.73 | TAAR1 (0.38) | SMN1; SMN2KMT2ABRD4AKT2TDO2 | |
| SCHEMBL348335 | 0.71 | TRPA1 (0.31) | — | |
| SCHEMBL12817155 | 0.70 | ADORA3 (0.30) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5485666 | 0.70 | — | — | |
| SCHEMBL3539990 | 0.69 | ALDH1A1 (0.35) | SMN1; SMN2HPGDKMT2AMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175423-A4 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | UNIV COLORADO STATE RES FOUND (US) | 2002-10-25 | — | — | EP | disclosed |
| EP-1175423-A1 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000053611-A1 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-14 | — | — | WO | disclosed |