Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340504 | 0.85 | KDM4E (0.45) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL2200675 | 0.81 | GABRA1 (0.55) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL10931666 | 0.77 | GABRA1 (0.39) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL17591957 | 0.77 | L3MBTL1 (0.46) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL10916615 | 0.77 | GABRA1 (0.46) | HTR1AGABRA1GABRB2SLC6A4SLC6A2 | |
| SCHEMBL475213 | 0.77 | L3MBTL1 (0.57) | GABRA1GABRB2SLC6A4SLC6A2SLC6A3 | |
| Nitrogen SCHEMBL10979594 | 0.77 | GABRA1 (0.50) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL11430105 | 0.75 | SLC6A2 (0.66) | SLC6A4SLC6A2SLC6A3MAPTL3MBTL1 | |
| SCHEMBL91279 | 0.75 | PNMT (0.62) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL6745155 | 0.74 | GABRA1 (0.43) | GABRA1GABRB2SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062221-A1 | PRETREATMENT FOR HAIR COLORING COMPOSITIONS AND METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2001-08-30 | — | — | WO | disclosed |