Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256292 | 0.79 | F2 (0.33) | PKMF2TSHRRAB9ANPC1 | |
| SCHEMBL14736214 | 0.78 | TSHR (0.41) | PKMBLMRECQLL3MBTL1F2 | |
| Benzamide SCHEMBL27945852 | 0.78 | L3MBTL1 (0.55) | PKMBLMRECQLL3MBTL1POLB | |
| SCHEMBL9350740 | 0.76 | F2 (0.37) | PKMBLMRECQLF2TSHR | |
| SCHEMBL135361 | 0.76 | KMT2A (0.50) | PKML3MBTL1F2TSHRMAPT | |
| SCHEMBL30081232 | 0.76 | MEN1 (0.37) | F2TSHRRAB9AKMT2AGAA | |
| SCHEMBL28785921 | 0.76 | MAPT (0.33) | L3MBTL1F2TSHRCYP3A4MAPT | |
| SCHEMBL1177045 | 0.76 | CES2 (0.34) | L3MBTL1F2TSHRCYP3A4RAB9A | |
| Biphenyl SCHEMBL3997420 | 0.73 | ALDH1A1 (0.45) | BLMRECQLL3MBTL1POLBCYP2C19 | |
| SCHEMBL6603475 | 0.72 | F2 (0.32) | PKMF2TSHRTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | claimed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | claimed |