Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135361 | 0.76 | KMT2A (0.50) | F2LMNATSHRCES2CES1 | |
| SCHEMBL11256292 | 0.75 | F2 (0.33) | F2LMNATSHRCES2CES1 | |
| SCHEMBL1025147 | 0.73 | CES1 (0.48) | F2LMNATSHRCES2CES1 | |
| SCHEMBL9350740 | 0.72 | F2 (0.37) | F2LMNATSHRCES2CES1 | |
| SCHEMBL28785921 | 0.72 | MAPT (0.33) | F2LMNATSHRCES2CES1 | |
| SCHEMBL1177045 | 0.72 | CES2 (0.34) | F2LMNATSHRCES2CES1 | |
| SCHEMBL30081232 | 0.72 | MEN1 (0.37) | F2LMNATSHRCES2CES1 | |
| SCHEMBL7738334 | 0.72 | PKM (0.37) | F2LMNATSHRCES2CES1 | |
| Benzamide SCHEMBL27945852 | 0.70 | L3MBTL1 (0.55) | LMNATSHRDAONAPRTALDH1A1 | |
| SCHEMBL28529893 | 0.70 | RAB9A (0.50) | F2ALDH1A1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308446-B1 | 5-(alkylidene-cycloalkyl)- and 5-(alkylidene-heterocyclyl)-pyrazoles | PFIZER PROD INC (US) | 2004-12-08 | — | — | EP | disclosed |