Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Butylated Hydroxytoluene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TYR | P14679 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylated Hydroxytoluene SCHEMBL28513763 | 0.97 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL864243 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL17835978 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL4826096 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL6908300 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL23090058 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL20455508 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL6901302 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL4820691 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TYRCA2POLB | |
| Butylated Hydroxytoluene SCHEMBL17836004 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TYRCA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112417782-B | Method for estimating circulation multiplying power of working medium in two loops of steam generator | 上海交通大学 | 2022-04-26 | — | — | CN | claimed |
| CN-112699523-B | Method and device for estimating vaporization starting height of working medium in secondary loop of steam generator | 上海交通大学 | 2022-04-26 | — | — | CN | claimed |
| CN-112380713-B | Method for estimating temperature distribution of metal wall of inverted U-shaped tube of steam generator | 上海交通大学 | 2022-03-22 | — | — | CN | claimed |
| CN-112417681-B | Estimation method for primary and secondary side convective heat transfer coefficient distribution of steam generator | 上海交通大学 | 2022-03-22 | — | — | CN | claimed |
| CN-112417676-B | Key variable estimation method based on nuclear power steam generator distribution parameter model | 上海交通大学 | 2022-02-25 | — | — | CN | claimed |
| CN-113754509-A | Method for preparing conjugated diene with single stereo configuration from allyl alcohol compound | 中山大学 | 2021-12-07 | — | — | CN | claimed |
| US-8552182-B2 | Method for producing a 3-(substituted-oxy)-4-pyridazinol derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-10-08 | — | — | US | claimed |
| US-20120184736-A1 | METHOD FOR PRODUCING A 3-(SUBSTITUTED-OXY)-4-PYRIDAZINOL DERIVATIVE | MITSUI CHEMICALS AGRO, INC (JP) | 2012-07-19 | — | — | US | claimed |
| WO-2025245187-A1 | COMPOSITION OF AND METHOD OF EXTRACTION OF ULVA GEL FROM SEAWEED POLYSACCHARIDE AND PROTEIN | BLUE EVOLUTION INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| CN-112699523-B | Method and device for estimating vaporization starting height of working medium in secondary loop of steam generator | 上海交通大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-112417782-B | Method for estimating circulation multiplying power of working medium in two loops of steam generator | 上海交通大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-112417681-B | Estimation method for primary and secondary side convective heat transfer coefficient distribution of steam generator | 上海交通大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-112380713-B | Method for estimating temperature distribution of metal wall of inverted U-shaped tube of steam generator | 上海交通大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-112417676-B | Key variable estimation method based on nuclear power steam generator distribution parameter model | 上海交通大学 | 2022-02-25 | — | — | CN | disclosed |
| EP-0663001-A1 | FUEL ADDITIVES | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-07-19 | — | — | EP | disclosed |
| WO-1995004119-A1 | FUEL ADDITIVES | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |
| US-4351759-A | OXIDATION RESISTANCE, OLEFIN POLYMERS | CIBA-GEIGY CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4288391-A | STABILIZERS FOR POLYMERS AND LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4196117-A | Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| US-3976677-A | Process for carboxylating organic substrates with carbon dioxide in hydrocarbon solvents | MONTEDISON S.P.A. (IT) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184736-A1 | METHOD FOR PRODUCING A 3-(SUBSTITUTED-OXY)-4-PYRIDAZINOL DERIVATIVE | CYP4F3, CYP4F2, PNPO | PTGS1 633/4885PTGS2 329/4885SMN1; SMN2 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.