SCHEMBL9300787

SCHEMBL9300787

C=C(c1ccccc1)P(=O)(OCCCl)OCCCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.38
TRPA1 O75762 1/20 0.37
MAPK1 P28482 1/20 0.37
GSK3B P49841 1/20 0.37
HIF1A Q16665 1/20 0.37
LMNA P02545 2/20 0.35
F2 P00734 1/20 0.35
CA2 P00918 1/20 0.35
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SRC P12931 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
NR1I2 O75469 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738533 0.79 NR1I2 (0.53) ALDH1A1SMN1; SMN2LMNATSHRPOLB
SCHEMBL11318778 0.76 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2LMNATSHRPOLB
SCHEMBL11318917 0.72 ALDH1A1 (0.40) ALDH1A1
SCHEMBL9300378 0.72 LMNA (0.47) ALDH1A1SMN1; SMN2LMNAF2CA2
SCHEMBL6910717 0.71 ALDH1A1 (0.52) ALDH1A1
SCHEMBL11308706 0.71 ALDH1A1 (0.54) ALDH1A1CA2TDP1MEN1KMT2A
Biphenyl SCHEMBL27757944 0.69 SRC (0.45) ALDH1A1SMN1; SMN2TSHRSRCNPC1
SCHEMBL10940660 0.69 ALDH1A1 (0.50) ALDH1A1
SCHEMBL8710959 0.69 CA2 (0.42) ALDH1A1SMN1; SMN2TRPA1MAPK1GSK3B
SCHEMBL28621705 0.68 MEN1 (0.66) ALDH1A1SMN1; SMN2LMNACA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5310808-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-05-10 US disclosed
US-5292817-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-03-08 US disclosed
US-4560618-A VINYL CHLORIDE-ETHYLHEXYL ACRYLATE-BIS(HYDROCARBYL)VINYL PHOSPHONATE TERPOLYMER; INTERNAL PLASTICIZING STAUFFER CHEMICAL COMPANY (US) 1985-12-24 US disclosed
EP-0011415-B1 VAPOUR BARRIER FILMS STAUFFER CHEMICAL COMPANY (US) 1984-08-15 EP disclosed
US-4444969-A Fire retardant copolymer from bis(hydrocarbyl)vinyl phosphonate ATLANTIC RICHFIELD COMPANY (US) 1984-04-24 US disclosed
US-4299940-A Process for the control of free radical polymerization STAUFFER CHEMICAL COMPANY (US) 1981-11-10 US disclosed
EP-0011415-A1 Vapour barrier films STAUFFER CHEMICAL COMPANY (US) 1980-05-28 EP disclosed
EP-0004391-A1 Vinyl film/substrate laminate STAUFFER CHEMICAL COMPANY (US) 1979-10-03 EP disclosed
US-4147853-A ALKYL ACRYLATE, DIHYDROCARBYL VINYLPHOSPHONATE STAUFFER CHEMICAL COMPANY (US) 1979-04-03 US disclosed
US-4129710-A Fire retardant copolymer of triallyl phosphate and a bis (hydrocarbyl) vinylphosphonate STAUFFER CHEMICAL COMPANY (US) 1978-12-12 US disclosed
US-3992481-A Fire retardant thermoplastic polymer compositions STAUFFER CHEMICAL COMPANY (US) 1976-11-16 US disclosed
US-3992482-A Fire retardant thermoplastic polymer compositions STAUFFER CHEMICAL COMPANY (US) 1976-11-16 US disclosed
US-3991134-A Fire retardant thermoplastic polymer compositions STAUFFER CHEMICAL COMPANY (US) 1976-11-09 US disclosed
US-3983294-A VINYL CHLORIDE-VINYL ACETATE-VINYL-PHOSPHONATE COPOLYMER STAUFFER CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3965216-A BIS(HYDROCARBYL) VINYL PHOSPHONATE STAUFFER CHEMICAL COMPANY (US) 1976-06-22 US disclosed
US-3948826-A COPOLYMER OF VINYL CHLORIDE AND A BIS(HYDROCARBYL) VINYLPHOSPHATE STAUFFER CHEMICAL COMPANY (US) 1976-04-06 US disclosed
US-3948842-A Fire retardant polymeric additives of vinylidene halides with bis(hydrocarbyl) vinyl phosphonates and C1 -C20 alkylesters of acrylic and methacrylic acids STAUFFER CHEMICAL COMPANY (US) 1976-04-06 US disclosed
US-3943085-A HYDROCARBYL VINYL PHOSPHONATE-VINYL OR VINYLIDENE HALIDE, FLAME RETARDANT STAUFFER CHEMICAL COMPANY (US) 1976-03-09 US disclosed
US-3943113-A FIRE RETARDANT STAUFFER CHEMICAL COMPANY (US) 1976-03-09 US disclosed
US-3935149-A BIS(HYDROCARBYL) VINYL PHOSPHONATE, VINYL OR VINYLIDENE HALIDE STAUFFER CHEMICAL COMPANY (US) 1976-01-27 US disclosed