Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738828 | 0.86 | LMNA (0.51) | FTOLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL6838753 | 0.84 | FTO (0.41) | FTOLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL1837301 | 0.81 | MEN1 (0.43) | FTOLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL29525901 | 0.81 | MEN1 (0.43) | FTOLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL7780203 | 0.80 | FTO (0.38) | FTOMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12120382 | 0.80 | CFTR (0.37) | FTOLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL13450786 | 0.79 | FTO (0.38) | FTOACHEALDH1A1TP53 | |
| SCHEMBL1838042 | 0.77 | FTO (0.47) | FTOLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL7740730 | 0.77 | LMNA (0.35) | LMNAMAPTPOLBL3MBTL1MEN1 | |
| SCHEMBL7751772 | 0.77 | DHFR (0.40) | FTOLMNAMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410678-B1 | HYDROXYL END GROUPS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1149852-A1 | AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE | TEIJIN LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |